In 'The Einstein Approximation' (season 3, episode 14), Sheldon Cooper, Super Genius, can't seem to get his brain to work properly. Stimulating the superior colliculus of his brain with peripheral, fleeting glimpses doesn't work (and don't you wonder why?) Days without sleep doesn't work. But working as a busboy at the Cheesecake Factory somehow works!! He drops a pile of dishes and - whammo! The patrons applaud as an insult because he dropped the dishes, but he then realized the solution to the problem! The electrons act as a wave!! And THAT is when those dolts should applaud!!